DAZ3 antibody (C-Term)

Catalog No. ABIN656239

Product Details anti-DAZ3 Antibody

Target: DAZ3 (Deleted In Azoospermia 3 (DAZ3))

Binding Specificity: AA 445-474, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAZ3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DAZ3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human DAZ3.

Clone: RB31085

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: DAZ3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for DAZ3

Target: DAZ3 (Deleted In Azoospermia 3 (DAZ3))

Alternative Name: DAZ3 (DAZ3 Products)

Synonyms: pDP1679 antibody, DAZ3 antibody, DAZ2 antibody, deleted in azoospermia 3 antibody, deleted in azoospermia protein 3 antibody, DAZ3 antibody, LOC738636 antibody

Background: This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat.

Molecular Weight: 54989

Gene ID: 57054

NCBI Accession: NP_065097

UniProt: Q9NR90