ITGA5 antibody (AA 575-602)

Catalog No. ABIN656138

Product Details anti-ITGA5 Antibody

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Binding Specificity: AA 575-602

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ITGA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 575-602 amino acids from the Central region of human ITGA5.

Clone: RB20677

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: ITGA5 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

References for anti-ITGA5 antibody (ABIN656138)

Hu, Fang, Wang, Luk, Thamphiwatana, Dehaini, Nguyen, Angsantikul, Wen, Kroll, Carpenter, Ramesh, Qu, Patel, Zhu, Shi, Hofman, Chen, Gao, Zhang, Chien, Zhang: "Nanoparticle biointerfacing by platelet membrane cloaking." in: Nature, Vol. 526, Issue 7571, pp. 118-21, (2015) (PubMed).

Target Details for ITGA5

Target: ITGA5 (Integrin, alpha 5 (ITGA5))

Alternative Name: ITGA5 (ITGA5 Products)

Background: The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq].

Molecular Weight: 114536

Gene ID: 3678

NCBI Accession: NP_002196

UniProt: P08648

Pathways: Integrin Complex