MED14 antibody (AA 586-615)

Catalog No. ABIN656136

Product Details anti-MED14 Antibody

Target: MED14 (Mediator Complex Subunit 14 (MED14))

Binding Specificity: AA 586-615

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED14 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MED14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-615 amino acids from the Central region of human MED14.

Clone: RB20179

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:4000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: MED14 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for MED14

Target: MED14 (Mediator Complex Subunit 14 (MED14))

Alternative Name: MED14 (MED14 Products)

Synonyms: CG12031 antibody, Dmel\\CG12031 antibody, Med14 antibody, Trap170 antibody, dTRAP170 antibody, p160 antibody, EXLM1 antibody, crsp150 antibody, crsp2 antibody, trap170 antibody, wu:fd21c05 antibody, wu:fk28h11 antibody, CRSP2 antibody, NV18605 antibody, CRSP150 antibody, CSRP antibody, CXorf4 antibody, DRIP150 antibody, RGR1 antibody, TRAP170 antibody, 9930001L01Rik antibody, AU041628 antibody, Crsp2 antibody, ENSMUSG00000073278 antibody, Gm641 antibody, ORF1 antibody, RGD1560170 antibody, Mediator complex subunit 14 antibody, mediator complex subunit 14 antibody, mediator of RNA polymerase II transcription subunit 14 antibody, transcriptional regulation antibody, MED14 antibody, med14 antibody, LOC100113592 antibody, Med14 antibody, RGR1 antibody

Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.

Molecular Weight: 160607

Gene ID: 9282

NCBI Accession: NP_004220

UniProt: O60244

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha