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Glutathione Reductase antibody (C-Term)

Name: Glutathione Reductase antibody (C-Term)
SKU: ABIN655985
Price: 451 USD
Availability: InStock

GSR Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB31981 unconjugated

GSR Antibody (C-term) (ABIN655985 and ABIN2845369) western blot analysis in NCI- cell line lysates (35 μg/lane). (Glutathione Reductase antibody (C-Term))

GSR Antibody (C-term) (ABIN655985 and ABIN2845369) flow cytometric analysis of NCI- cells (right histogram) compared to a negative control -Rabbit IgG alone (left histogram). (Glutathione Reductase antibody (C-Term))

FACS

Confocal immunofluorescent analysis of GSR Antibody (C-term) (ABIN655985 and ABIN2845369) with NCI- cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (Glutathione Reductase antibody (C-Term))

GSR Antibody (C-term) (ABIN655985 and ABIN2845369) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. (Glutathione Reductase antibody (C-Term))

IHC (p)

4 images

Catalog No. ABIN655985

Datasheet as PDF

Target See all Glutathione Reductase (GSR) Antibodies

Glutathione Reductase (GSR)
Binding Specificity
15

15

6

5

4

3

3

2

2

2

2

1

1

1

1

1
AA 380-408, C-Term
Reactivity
53

26

21

6

2

2

2

1

1

1

1

1

1

1

1

1

1

1
Human
Host
72

8
Rabbit
Compatible Secondaries
Clonality
72

8
Polyclonal
Conjugate
35

6

5

4

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This Glutathione Reductase antibody is un-conjugated
Application
51

26

26

26

22

16

10

10

10

9

6

4

2

2

2

2

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This GSR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-408 amino acids from the C-terminal region of human GSR.

Clone

RB31981

Isotype

IgG

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GSR Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

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GSR Reactivity: Human WB, ELISA, IHC (p), RNAi Host: Mouse Monoclonal 6B4 unconjugated

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GSR Reactivity: Human, Rat, Mouse WB, IHC, ELISA, ICC, FACS Host: Rabbit Polyclonal unconjugated

anti-Glutathione Reductase (GSR) (AA 7-246) antibody
GSR Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Glutathione Reductase (GSR) (AA 1-522) antibody
GSR Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

anti-Glutathione Reductase (GSR) (AA 387-416), (C-Term) antibody
GSR Reactivity: Human WB, IF, IHC (p), FACS, EIA Host: Rabbit Polyclonal unconjugated

anti-Glutathione Reductase (GSR) (AA 47-219) antibody
GSR Reactivity: Human IHC, ELISA, IF Host: Rabbit Polyclonal unconjugated

anti-Glutathione Reductase (GSR) (AA 421-522) antibody
GSR Reactivity: Human, Mouse WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-Glutathione Reductase (GSR) antibody
GSR Reactivity: Human, Rat, Mouse WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated

Application Notes

IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions

For Research Use only
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative

Sodium azide

Precaution of Use

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage

4 °C,-20 °C

Storage Comment

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date

6 months
Target

Glutathione Reductase (GSR)

Alternative Name

GSR (GSR Products)

Background

This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

Molecular Weight

56257

Gene ID

2936

NCBI Accession

NP_000628, NP_001182031, NP_001182032, NP_001182033

UniProt

P00390

Pathways

Thyroid Hormone Synthesis, Cell RedoxHomeostasis