Tetraspanin 7 antibody

Catalog No. ABIN6559816

Product Details anti-Tetraspanin 7 Antibody

Target: Tetraspanin 7 (TSPAN7)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tetraspanin 7 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Specificity: The mouse monoclonal antibody B2D recognizes an extracellular epitope of CD231 (TALLA-1, tetraspanin 7), a transmembrane glycoprotein expressed in neuronal tissue and T-ALL.

Cross-Reactivity (Details): Human, Other not determined

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: Human T-ALL cell line THP-6

Clone: B2D

Isotype: IgG1

Application Details

Application Notes: Immunohistochemistry: Positive control: brain.
Flow cytometry: Recommended dilution: 1-4 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for Tetraspanin 7

Target: Tetraspanin 7 (TSPAN7)

Alternative Name: CD231 (TSPAN7 Products)

Synonyms: A15 antibody, CCG-B7 antibody, CD231 antibody, DXS1692E antibody, MRX58 antibody, MXS1 antibody, TALLA-1 antibody, TM4SF2 antibody, TM4SF2b antibody, 1200014P11Rik antibody, AI323365 antibody, Cd231 antibody, Mxs1 antibody, PE31 antibody, R74651 antibody, TALLA antibody, Tm4sf2 antibody, tm4sf2 antibody, zgc:63823 antibody, wu:fa11g01 antibody, wu:fd18e11 antibody, wu:fl39g07 antibody, a15 antibody, ccg-b7 antibody, cd231 antibody, mrx58 antibody, mxs1 antibody, talla-1 antibody, tspan7 antibody, tetraspanin 7 antibody, tetraspanin 7 L homeolog antibody, TSPAN7 antibody, Tspan7 antibody, tspan7 antibody, tspan7.L antibody

Background: Tetraspanin 7,CD231 (TALLA-1, T-ALL-asociated antigen 1), also known as tetraspanin 7, is a 150 kDa (under reducing conditions 32-45 kDa) transmembrane glycoprotein of tetraspanin family, expressed in T-type acute lymphoblastic leukemia, neuroblastoma, and neuronal tissue. Mutations of CD231 gene are associated with X-linked mental retardation, Huntington´s chorea, and myotonic dystrophy. CD231 interacts with integrins and may have a role in the control of neurite outgrowth. Antibodies to CD231 are important for detection of T-ALL and are potential targets of its treatment.,TSPAN7, TALLA-1, MXS1, MRX58, TM4SF2

Gene ID: 7102

UniProt: P41732