MED7 antibody (AA 83-111)

Catalog No. ABIN655901

Product Details anti-MED7 Antibody

Target: MED7 (Mediator Complex Subunit 7 (MED7))

Binding Specificity: AA 83-111

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED7 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Predicted Reactivity: B, M, Pig

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MED7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the Central region of human MED7.

Clone: RB18104

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for MED7

Target: MED7 (Mediator Complex Subunit 7 (MED7))

Alternative Name: MED7 (MED7 Products)

Synonyms: ARC34 antibody, CRSP33 antibody, CRSP9 antibody, 1110063B05Rik antibody, Crsp33 antibody, Crsp9 antibody, crsp9 antibody, wu:fd99d12 antibody, zgc:56241 antibody, crsp9-A antibody, med7-a antibody, mediator complex subunit 7 antibody, mediator complex subunit 7 L homeolog antibody, mediator complex subunit antibody, mediator complex subunit Med7 antibody, MED7 antibody, Med7 antibody, med7 antibody, med7.L antibody

Background: The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

Molecular Weight: 27245

Gene ID: 9443

NCBI Accession: NP_001094286, NP_004261

UniProt: O43513

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha