WTIP antibody (AA 243-271)

Catalog No. ABIN655782

Product Details anti-WTIP Antibody

Target: WTIP (Wilms Tumor 1 Interacting Protein (WTIP))

Binding Specificity: AA 243-271

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WTIP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This WTIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids of human WTIP.

Clone: RB29854

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:500. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for WTIP

Target: WTIP (Wilms Tumor 1 Interacting Protein (WTIP))

Alternative Name: WTIP (WTIP Products)

Synonyms: RGD1306411 antibody, si:ch211-79l17.3 antibody, WT1 interacting protein antibody, Wilms tumor 1 interacting protein antibody, WT1 interacting protein L homeolog antibody, WT1-interacting protein antibody, Wtip antibody, WTIP antibody, wtip antibody, wtip.L antibody

Background: WTIP may monitor slit diaphragm protein assembly, a specialized adherens junction characteristic of podocytes. In case of podocyte injury, it shuttles into the nucleus and acts as a transcription regulator that represses WT1-dependent transcription regulation, thereby translating changes in slit diaphragm structure into altered gene expression and a less differentiated phenotype (By similarity).

Molecular Weight: 45124

Gene ID: 126374

NCBI Accession: NP_001073905

UniProt: A6NIX2