This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SCEL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-289 amino acids from the Central region of human SCEL.
The protein encoded by this gene is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes to the periphery of cells and may function in the assembly or regulation of proteins in the cornified envelope. Transcript variants encoding different isoforms exist. A transcript variant utilizing an alternative polyA signal has been described in the literature, but its full-length nature has not been determined.