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CPT1C antibody (C-Term)

CPT1C Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB19024 unconjugated
Catalog No. ABIN655406
  • Target See all CPT1C Antibodies
    CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))
    Binding Specificity
    • 15
    • 11
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 752-782, C-Term
    Reactivity
    • 58
    • 6
    • 3
    Human
    Host
    • 59
    • 1
    • 1
    Rabbit
    Clonality
    • 60
    • 1
    Polyclonal
    Conjugate
    • 20
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CPT1C antibody is un-conjugated
    Application
    • 46
    • 36
    • 13
    • 13
    • 12
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CPT1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 752-782 amino acids from the C-terminal region of human CPT1C.
    Clone
    RB19024
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CPT1C Primary Antibody
  • Application Notes
    WB: 1:1000. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    CPT1C (Carnitine Palmitoyltransferase 1C (CPT1C))
    Alternative Name
    CPT1C (CPT1C Products)
    Synonyms
    6530437J22Rik antibody, 9630004I06Rik antibody, CATL1 antibody, CPT1-B antibody, CPT1P antibody, CPTI-B antibody, CPTIC antibody, CPT IC antibody, carnitine palmitoyltransferase 1c antibody, carnitine palmitoyltransferase 1C antibody, Cpt1c antibody, CPT1C antibody
    Background
    The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.
    Molecular Weight
    90989
    Gene ID
    126129
    NCBI Accession
    NP_001129524, NP_001186681, NP_001186682, NP_689572
    UniProt
    Q8TCG5
    Pathways
    AMPK Signaling, Monocarboxylic Acid Catabolic Process
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