KDM4C antibody (C-Term)

Catalog No. ABIN655391

Product Details anti-KDM4C Antibody

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Binding Specificity: AA 1023-1056, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KDM4C antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This JMJD2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1023-1056 amino acids from the C-terminal region of human JMJD2C.

Clone: RB10796

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. FC: 1:25. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for KDM4C

Target: KDM4C (Lysine (K)-Specific Demethylase 4C (KDM4C))

Alternative Name: JMJD2C (KDM4C Products)

Synonyms: JMJD2C antibody, GASC1 antibody, JHDM3C antibody, TDRD14C antibody, bA146B14.1 antibody, 2410141F18Rik antibody, AA517467 antibody, Gasc1 antibody, Jmjd2c antibody, lysine demethylase 4C antibody, jumonji domain containing 2c antibody, lysine (K)-specific demethylase 4C antibody, KDM4C antibody, Jmjd2c antibody, kdm4c antibody, Kdm4c antibody

Background: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.

Molecular Weight: 119982

Gene ID: 23081

NCBI Accession: NP_001140166, NP_001140167, NP_001140168, NP_055876

UniProt: Q9H3R0

Pathways: Nuclear Hormone Receptor Binding, Warburg Effect