COPE
(Coatomer Protein Complex, Subunit epsilon (COPE))
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Conjugate
This COPE antibody is un-conjugated
Application
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Clone
RB19580
Binding Specificity
AA 273-300, C-Term
Predicted Reactivity
C, Ha, M
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This COPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 273-300 amino acids from the C-terminal region of human COPE.
COPE
Reactivity: Human
ELISA
Host: Rabbit
Polyclonal
Biotin
Application Notes
IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target
COPE
(Coatomer Protein Complex, Subunit epsilon (COPE))
Alternative Name
COPE
Background
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.