YOD1 antibody (C-Term)

Catalog No. ABIN655251

Product Details anti-YOD1 Antibody

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Binding Specificity: AA 319-347, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YOD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: C, Zf

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This YOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 319-347 amino acids from the C-terminal region of human YOD1.

Clone: RB29107

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:2000. WB: 1:1000. IHC-P-Leica: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-YOD1 antibody (ABIN655251)

Bernardi, Williams, Inoue, Schultz, Tsai: "A deubiquitinase negatively regulates retro-translocation of nonubiquitinated substrates." in: Molecular biology of the cell, Vol. 24, Issue 22, pp. 3545-56, (2013) (PubMed).

Target Details for YOD1

Target: YOD1 (Ubiquitin Thioesterase OTU1 (YOD1))

Alternative Name: YOD1 (YOD1 Products)

Background: Deubiquitinating enzymes (DUBs, see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. DUBA8 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM].

Molecular Weight: 38322

Gene ID: 55432

NCBI Accession: NP_001263249, NP_061036

UniProt: Q5VVQ6

Pathways: ER-Nucleus Signaling