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Endothelin 3 antibody (C-Term)

EDN3 Reactivity: Human WB Host: Rabbit Polyclonal RB18967 unconjugated
Catalog No. ABIN655169
  • Target See all Endothelin 3 (EDN3) Antibodies
    Endothelin 3 (EDN3)
    Binding Specificity
    • 9
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    AA 168-197, C-Term
    Reactivity
    • 35
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 34
    • 3
    Rabbit
    Clonality
    • 35
    • 2
    Polyclonal
    Conjugate
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Endothelin 3 antibody is un-conjugated
    Application
    • 26
    • 18
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This EDN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human EDN3.
    Clone
    RB18967
    Isotype
    Ig Fraction
    Top Product
    Discover our top product EDN3 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    Endothelin 3 (EDN3)
    Alternative Name
    EDN3 (EDN3 Products)
    Synonyms
    et-3 antibody, EDN3 antibody, ET-3 antibody, ET3 antibody, HSCR4 antibody, PPET3 antibody, WS4B antibody, 114CH19 antibody, ls antibody, tmgc48 antibody, Et3 antibody, RGD1564825 antibody, preproET-3 antibody, endothelin-3 L homeolog antibody, endothelin 3 antibody, edn3.L antibody, EDN3 antibody, Edn3 antibody
    Background
    The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
    Molecular Weight
    25454
    Gene ID
    1908
    NCBI Accession
    NP_000105, NP_996915, NP_996916, NP_996917
    UniProt
    P14138
    Pathways
    Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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