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MAP3K12 antibody
MAP3K12
Reactivity: Human
WB, IHC (p)
Host: Rabbit
Polyclonal
RB15965
unconjugated
Product Details anti-MAP3K12 Antibody
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Target
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MAP3K12
(Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))
Reactivity
All reactivities for MAP3K12 antibodies
Human
Host
All hosts for MAP3K12 antibodies
Rabbit
Clonality
All clonalities for MAP3K12 antibodies
Polyclonal
Conjugate
All conjugates for MAP3K12 antibodies
This MAP3K12 antibody is un-conjugated
Application
All applications for MAP3K12 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This DLK Antibody is generated from rabbits immunized with a recombinant protein of human DLK.
Clone
RB15965
Isotype
Ig Fraction
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Discover our top product MAP3K12 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB: 1:1000. IHC-P: 1:50~100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for MAP3K12
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Target
MAP3K12
(Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))
Alternative Name
DLK (MAP3K12 Products )
Synonyms
DLK antibody, MEKK12 antibody, MUK antibody, ZPK antibody, ZPKP1 antibody, PK antibody, Zpk antibody, zgc:77370 antibody, MGC151798 antibody, dlk antibody, map3k12 antibody, map3k12a antibody, mekk12 antibody, muk antibody, zpk antibody, zpkp1 antibody, DKFZp459K2433 antibody, map3k12-a antibody, map3k12-b antibody, map3k12b antibody, mitogen-activated protein kinase kinase kinase 12 antibody, mitogen activated protein kinase kinase kinase 12 antibody, mitogen-activated protein kinase kinase kinase 12 S homeolog antibody, mitogen-activated protein kinase kinase kinase 12 L homeolog antibody, MAP3K12 antibody, Map3k12 antibody, map3k12 antibody, map3k12.S antibody, map3k12.L antibody
Background
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes, it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance, this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.
Molecular Weight
41300
Gene ID
8788
NCBI Accession
NP_003827
UniProt
P80370
Pathways
MAPK Signaling
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