This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ETFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the C-terminal region of human ETFA.
2010200I21Rik antibody, D9Ertd394e antibody, ETF antibody, EMA antibody, GA2 antibody, MADD antibody, cb1020 antibody, fd06h11 antibody, wu:fd06h11 antibody, ema antibody, ga2 antibody, madd antibody, electron transfer flavoprotein alpha subunit antibody, electron-transfer-flavoprotein, alpha polypeptide antibody, putative electron-transfer-flavoprotein,alpha polypeptide antibody, electron transfer flavoprotein subunit alpha, mitochondrial antibody, electron transferring flavoprotein, alpha polypeptide antibody, electron transfer flavoprotein alpha subunit L homeolog antibody, ETFA antibody, Tc00.1047053503559.109 antibody, Tc00.1047053511693.90 antibody, LMJF_28_1140 antibody, LOC100194695 antibody, etfa antibody, Etfa antibody, etfa.L antibody
Background
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.