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CAD antibody (AA 780-809)
CAD
Reactivity: Human
WB, IHC (p), FACS
Host: Rabbit
Polyclonal
RB18384
unconjugated
Product Details anti-CAD Antibody
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Target
See all CAD Antibodies
CAD
(Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
Binding Specificity
All epitopes for CAD antibodies
AA 780-809
Reactivity
All reactivities for CAD antibodies
Human
Host
All hosts for CAD antibodies
Rabbit
Clonality
All clonalities for CAD antibodies
Polyclonal
Conjugate
All conjugates for CAD antibodies
This CAD antibody is un-conjugated
Application
All applications for CAD antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
Predicted Reactivity
M
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CAD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-809 amino acids from the Central region of human CAD.
Clone
RB18384
Isotype
Ig Fraction
Alternatives
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anti-Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD) (AA 2018-2067) antibody
CAD
Reactivity: Human, Mouse, Rat, Dog, Rabbit, Horse, Cow, Zebrafish (Danio rerio), Bat, Hamster, Monkey
WB
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB: 1:2000. WB: 1:2000. WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. IHC-P: 1:25. FC: 1:25
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for CAD
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Target
CAD
(Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))
Alternative Name
CAD (CAD Products )
Synonyms
Cpad antibody, AU018859 antibody, 2410008J01Rik antibody, cb456 antibody, wu:fc30c12 antibody, wu:fc33d01 antibody, wu:fc67g02 antibody, si:dkey-221h15.3 antibody, CAD antibody, xcad antibody, carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase antibody, CAD antibody, Cad antibody, cad antibody
Background
The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.
Molecular Weight
242984
Gene ID
790
NCBI Accession
NP_004332
UniProt
P27708
Pathways
Production of Molecular Mediator of Immune Response , Ribonucleoside Biosynthetic Process
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