BCLAF1 antibody (C-Term)

Catalog No. ABIN654941

Product Details anti-BCLAF1 Antibody

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Binding Specificity: AA 658-687, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCLAF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This BCLAF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 658-687 amino acids from the C-terminal region of human BCLAF1.

Clone: RB25182

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for BCLAF1

Target: BCLAF1 (BCL2-Associated Transcription Factor 1 (BCLAF1))

Alternative Name: BCLAF1 (BCLAF1 Products)

Synonyms: Aa2-041 antibody, Fam54a antibody, Mtfr2 antibody, 2610102K23Rik antibody, 2700025J07Rik antibody, 2810454G14Rik antibody, 5730534O06Rik antibody, AI450190 antibody, AW556225 antibody, Btf antibody, mKIAA0164 antibody, btf antibody, bk211l9.1 antibody, BCLAF1 antibody, DKFZp468F0113 antibody, BTF antibody, bK211L9.1 antibody, BCL2-associated transcription factor 1 antibody, BCL2 associated transcription factor 1 antibody, mitochondrial fission regulator 2 antibody, Bclaf1 antibody, BCLAF1 antibody, bclaf1 antibody, MTFR2 antibody

Background: This gene encodes a transcriptional repressor that interacts with several members of the BCL2 family of proteins. Overexpression of this protein induces apoptosis, which can be suppressed by co-expression of BCL2 proteins. The protein localizes to dot-like structures throughout the nucleus, and redistributes to a zone near the nuclear envelope in cells undergoing apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 106122

Gene ID: 9774

NCBI Accession: NP_001070908, NP_001070909, NP_055554

UniProt: Q9NYF8

Pathways: Positive Regulation of Response to DNA Damage Stimulus