CEP164 antibody (N-Term)

Catalog No. ABIN654934

Product Details anti-CEP164 Antibody

Target: CEP164 (Centrosomal Protein 164kDa (CEP164))

Binding Specificity: AA 246-274, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CEP164 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CE164 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-274 amino acids from the N-terminal region of human CE164.

Clone: RB24951

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CEP164

Target: CEP164 (Centrosomal Protein 164kDa (CEP164))

Alternative Name: CE164 (CEP164 Products)

Synonyms: AI450905 antibody, BC027092 antibody, D030051D21 antibody, mKIAA1052 antibody, RGD1560988 antibody, RGD1561243 antibody, NPHP15 antibody, centrosomal protein 164 antibody, CEP164 antibody, Cep164 antibody

Background: Plays a role in microtubule organization and/or maintenance for the formation of primary cilia (PC), a microtubule-based structure that protrudes from the surface of epithelial cells. Plays a critical role in G2/M checkpoint and nuclear divisions. A key player in the DNA damage-activated ATR/ATM signaling cascade since it is required for the proper phosphorylation of H2AX, RPA,CHK2 and CHK1. Plays a critical role in chromosome segregation, acting as a mediator required for the maintenance of genomic stability through modulation of MDC1, RPA and CHK1.

Molecular Weight: 164314

Gene ID: 22897

NCBI Accession: NP_001258862, NP_055771

UniProt: Q9UPV0

Pathways: M Phase