SPACA1 antibody (N-Term)

Catalog No. ABIN654730

Product Details anti-SPACA1 Antibody

Target: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Binding Specificity: AA 46-74, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPACA1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SACA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human SACA1.

Clone: RB25586

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SPACA1

Target: SPACA1 (Sperm Acrosome Associated 1 (SPACA1))

Alternative Name: SACA1 (SPACA1 Products)

Synonyms: SAMP32 antibody, 1700124L11Rik antibody, 4930540L03Rik antibody, sperm acrosome associated 1 antibody, SPACA1 antibody, Spaca1 antibody

Background: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively.

Molecular Weight: 32143

Gene ID: 81833

NCBI Accession: NP_112222

UniProt: Q9HBV2