CLPX antibody (C-Term)

Catalog No. ABIN654723

Product Details anti-CLPX Antibody

Target: CLPX (ClpX Caseinolytic Peptidase X (CLPX))

Binding Specificity: AA 449-477, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLPX antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CLPX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 449-477 amino acids from the C-terminal region of human CLPX.

Clone: RB24942

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-CLPX antibody (ABIN654723)

Gispert, Parganlija, Klinkenberg, Dröse, Wittig, Mittelbronn, Grzmil, Koob, Hamann, Walter, Büchel, Adler, Hrabé de Angelis, Busch, Zell, Reichert, Brandt, Osiewacz, Jendrach, Auburger: "Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors." in: Human molecular genetics, Vol. 22, Issue 24, pp. 4871-87, (2013) (PubMed).

Target Details for CLPX

Target: CLPX (ClpX Caseinolytic Peptidase X (CLPX))

Alternative Name: CLPX (CLPX Products)

Synonyms: AU014732 antibody, E330029I21 antibody, caseinolytic mitochondrial matrix peptidase chaperone subunit antibody, Clpx antibody, CLPX antibody

Background: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of clpP (By similarity).

Molecular Weight: 69224

Gene ID: 10845

NCBI Accession: NP_006651

UniProt: O76031