MPP1 antibody (AA 301-327)

Catalog No. ABIN654665

The Rabbit Polyclonal anti-MPP1 antibody has been validated for WB, FACS and IHC (p). It is suitable to detect MPP1 in samples from Human.

Quick Overview for MPP1 antibody (AA 301-327) (ABIN654665)

Target: MPP1 (Membrane Protein, Palmitoylated 1, 55kDa (MPP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPP1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB24290

Product Details anti-MPP1 Antibody

Binding Specificity: AA 301-327

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 301-327 amino acids from the Central region of human MPP1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for MPP1

Target: MPP1 (Membrane Protein, Palmitoylated 1, 55kDa (MPP1))

Alternative Name: MPP1

Background: This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 52296

Gene ID: 4354

NCBI Accession: NP_001159932, NP_001159933, NP_001159934, NP_002427

UniProt: Q00013