ATF7IP2 antibody (AA 318-347)

Catalog No. ABIN654466

Product Details anti-ATF7IP2 Antibody

Target: ATF7IP2 (Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2))

Binding Specificity: AA 318-347

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATF7IP2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MCAF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 318-347 amino acids from the Central region of human MCAF2.

Clone: RB28618

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ATF7IP2

Target: ATF7IP2 (Activating Transcription Factor 7 Interacting Protein 2 (ATF7IP2))

Alternative Name: MCAF2 (ATF7IP2 Products)

Synonyms: MCAF2 antibody, 4930558K11Rik antibody, BC018510 antibody, Get-1 antibody, PSM2 antibody, activating transcription factor 7 interacting protein 2 antibody, ATF7IP2 antibody, Atf7ip2 antibody

Background: Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone 'Lys-9' trimethylation activity (Probable).

Molecular Weight: 75764

Gene ID: 80063

NCBI Accession: NP_001243089, NP_079273

UniProt: Q5U623