DDX11 antibody (AA 656-683)

Catalog No. ABIN654411

Product Details anti-DDX11 Antibody

Target: DDX11 (DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11))

Binding Specificity: AA 656-683

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDX11 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DDX11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 656-683 amino acids from the Central region of human DDX11.

Clone: RB27628

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for DDX11

Target: DDX11 (DEAD/H (Asp-Glu-Ala-Asp/His) Box Polypeptide 11 (DDX11))

Alternative Name: DDX11 (DDX11 Products)

Synonyms: CHL1 antibody, CHLR1 antibody, KRG2 antibody, WABS antibody, 4732462I11Rik antibody, essa15a antibody, putative ATP-dependent RNA helicase DDX11-like protein 8 antibody, DEAD/H-box helicase 11 antibody, DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 antibody, LOC100448472 antibody, DDX11 antibody, Ddx11 antibody

Background: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX11 encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. DDX11 is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genome stability.

Molecular Weight: 108313

Gene ID: 1663

NCBI Accession: NP_001244073, NP_001244074, NP_004390, NP_689651

UniProt: Q96FC9

Pathways: ER-Nucleus Signaling