SAR1B antibody (AA 89-116)

Catalog No. ABIN654355

Product Details anti-SAR1B Antibody

Target: SAR1B (SAR1 Homolog B (SAR1B))

Binding Specificity: AA 89-116

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAR1B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B, Ha, M, Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SAR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids from the Central region of human SAR1B.

Clone: RB28097

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SAR1B

Target: SAR1B (SAR1 Homolog B (SAR1B))

Alternative Name: SAR1B (SAR1B Products)

Synonyms: SAR1 antibody, SAR1B antibody, SARA2 antibody, 2310075M17Rik antibody, 2900019I22Rik antibody, CMRD antibody, Sara1b antibody, Sara2 antibody, Sarb antibody, cmrd antibody, gtbpb antibody, sar1a antibody, sara2 antibody, SARA1B antibody, ANDD antibody, GTBPB antibody, zgc:73204 antibody, secretion associated Ras related GTPase 1B antibody, hypothetical protein antibody, SAR1 homolog B (S. cerevisiae) antibody, secretion associated, Ras related GTPase 1B L homeolog antibody, secretion associated, Ras related GTPase 1B antibody, SAR1B antibody, Sar1B antibody, sar1b antibody, Sar1b antibody, sar1b.L antibody

Background: The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 22410

Gene ID: 51128

NCBI Accession: NP_001028675, NP_057187

UniProt: Q9Y6B6

Pathways: Lipid Metabolism