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DENND1B antibody (N-Term)

DENND1B Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB28056 unconjugated
Catalog No. ABIN654339
  • Target See all DENND1B Antibodies
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    Binding Specificity
    • 15
    • 8
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 39-68, N-Term
    Reactivity
    • 31
    • 20
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 45
    • 1
    Rabbit
    Clonality
    • 46
    Polyclonal
    Conjugate
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DENND1B antibody is un-conjugated
    Application
    • 39
    • 16
    • 15
    • 13
    • 13
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This DENND1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the N-terminal region of human DENND1B.
    Clone
    RB28056
    Isotype
    Ig Fraction
  • Application Notes
    WB: 1:500. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    DENND1B (DENN/MADD Domain Containing 1B (DENND1B))
    Alternative Name
    DENND1B (DENND1B Products)
    Synonyms
    C1ORF18 antibody, C1orf218 antibody, FAM31B antibody, 4632404N19Rik antibody, 4930467M19Rik antibody, 6820401H01Rik antibody, F730008N07Rik antibody, Fam31b antibody, si:ch211-195i21.1 antibody, DENN domain containing 1B antibody, DENN/MADD domain containing 1B antibody, DENND1B antibody, dennd1b antibody, Dennd1b antibody
    Background
    Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).
    Molecular Weight
    86552
    Gene ID
    163486
    NCBI Accession
    NP_001182144, NP_001182145, NP_659414
    UniProt
    Q6P3S1
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