GGTLC2 antibody (AA 127-154)

Catalog No. ABIN654174

Product Details anti-GGTLC2 Antibody

Target: GGTLC2 (gamma-Glutamyltransferase Light Chain 2 (GGTLC2))

Binding Specificity: AA 127-154

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GGTLC2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M, Pig, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This GGTLC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-154 amino acids from the Central region of human GGTLC2.

Clone: RB24615

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for GGTLC2

Target: GGTLC2 (gamma-Glutamyltransferase Light Chain 2 (GGTLC2))

Alternative Name: GGTLC2 (GGTLC2 Products)

Synonyms: GGTL4 antibody, gamma-glutamyltransferase light chain 2 antibody, GGTLC2 antibody

Background: Gamma-glutamyltransferase-1 (GGT1, MIM 612346) is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. Autocatalytic cleavage of the GGT1 precursor polypeptide produces a heavy chain and a light chain that associate with each other to form the functional enzyme. Light chain-only GGTs, such as GGTLC2, contain a region corresponding to the GGT1 light chain, but they lack the membrane-anchoring heavy chain region (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM].

Molecular Weight: 23661

Gene ID: 91227

NCBI Accession: NP_954578

UniProt: Q14390