MED25 antibody (AA 112-140)

Catalog No. ABIN654162

Product Details anti-MED25 Antibody

Target: MED25 (Mediator Complex Subunit 25 (MED25))

Binding Specificity: AA 112-140

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED25 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MED25 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-140 amino acids of human MED25.

Clone: RB24225

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-MED25 antibody (ABIN654162)

Han, Rha, Chi: "MED25 is a mediator component of HNF4α-driven transcription leading to insulin secretion in pancreatic beta-cells." in: PLoS ONE, Vol. 7, Issue 8, pp. e44007, (2013) (PubMed).

Target Details for MED25

Target: MED25 (Mediator Complex Subunit 25 (MED25))

Alternative Name: MED25 (MED25 Products)

Synonyms: Arc92 antibody, CG12254 antibody, Dmel\\CG12254 antibody, LD07688 antibody, Med25 antibody, dARC92 antibody, dDrip97 antibody, med25 antibody, ACID1 antibody, ARC92 antibody, CMT2B2 antibody, P78 antibody, PTOV2 antibody, RGD1305137 antibody, 2610034E13Rik antibody, 2610529E18Rik antibody, ESTM2 antibody, X83308 antibody, zgc:63555 antibody, Mediator complex subunit 25 antibody, mediator complex subunit 25 antibody, mediator complex subunit 25 S homeolog antibody, MED25 antibody, med25 antibody, Med25 antibody, med25.S antibody

Background: This gene encodes a component of the transcriptional coactivator complex termed the Mediator complex. This complex is required for transcription of most RNA polymerase II-dependent genes. The encoded protein plays a role in chromatin modification and in preinitiation complex assembly. Mutations in this gene are associated with Charcot-Marie-Tooth disease type 2B2. [provided by RefSeq].

Molecular Weight: 78171

Gene ID: 81857

NCBI Accession: NP_112235

UniProt: Q71SY5

Pathways: Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response