DPAGT1 antibody (AA 286-315)

Catalog No. ABIN653925

Product Details anti-DPAGT1 Antibody

Target: DPAGT1 (Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) (DPAGT1))

Binding Specificity: AA 286-315

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPAGT1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DPAGT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-315 amino acids from the Central region of human DPAGT1.

Clone: RB23874

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-DPAGT1 antibody (ABIN653925)

Klein, Robb, Rushing, Liu, Belaya, Beeson: "Congenital myasthenic syndrome caused by mutations in DPAGT." in: Neuromuscular disorders : NMD, Vol. 25, Issue 3, pp. 253-6, (2015) (PubMed).

Target Details for DPAGT1

Target: DPAGT1 (Dolichyl-Phosphate (UDP-N-Acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P Transferase) (DPAGT1))

Alternative Name: DPAGT1 (DPAGT1 Products)

Synonyms: AU021132 antibody, Dpagt2 antibody, GPT antibody, Gnpta antibody, DPAGT2 antibody, G1PT antibody, GNPTA antibody, GTR2 antibody, ALG7 antibody, CDG-Ij antibody, CDG1J antibody, CMSTA2 antibody, D11S366 antibody, DGPT antibody, DPAGT antibody, UAGT antibody, UGAT antibody, dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) antibody, dolichyl-phosphate N-acetylglucosaminephosphotransferase 1 antibody, Dpagt1 antibody, DPAGT1 antibody

Background: DPAGT1 encoded by this gene is an enzyme that catalyzes the first step in the dolichol-linked oligosaccharide pathway for glycoprotein biosynthesis. This enzyme belongs to the glycosyltransferase family 4. This protein is an integral membrane protein of the endoplasmic reticulum. The congenital disorder of glycosylation type Ij is caused by mutation in the gene encoding this enzyme.

Molecular Weight: 46090

Gene ID: 1798

NCBI Accession: NP_001373

UniProt: Q9H3H5