CD1e antibody (AA 184-212)

Catalog No. ABIN653900

Product Details anti-CD1e Antibody

Target: CD1e

Binding Specificity: AA 184-212

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD1e antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CD1E antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 184-212 amino acids from the Central region of human CD1E.

Clone: RB26783

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CD1e

Target: CD1e

Alternative Name: CD1E (CD1e Products)

Synonyms: CD1A antibody, R2 antibody, CD1-e antibody, CD1e molecule antibody, CD1E antibody, Cd1e antibody

Background: CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members.

Molecular Weight: 43626

Gene ID: 913

NCBI Accession: NP_001036048, NP_001036049, NP_001036050, NP_001036051, NP_001036052, NP_001172036, NP_001172037, NP_001172039, NP_001172041, NP_001172042, NP_001172043, NP_001172044, NP_112155

UniProt: P15812