PYCR1 antibody (C-Term)

Catalog No. ABIN653849

Product Details anti-PYCR1 Antibody

Target: PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

Binding Specificity: AA 291-319, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PYCR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PYCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human PYCR1.

Clone: RB24671

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-PYCR1 antibody (ABIN653849)

Zeng, Zhu, Liao, Zhuo, Yang, Wu, Wang: "Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer." in: Medical oncology (Northwood, London, England), Vol. 34, Issue 2, pp. 27, (2017) (PubMed).

Target Details for PYCR1

Target: PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))

Alternative Name: PYCR1 (PYCR1 Products)

Synonyms: arcl2b antibody, p5c antibody, p5cr antibody, pig45 antibody, pp222 antibody, pro3 antibody, pycr antibody, ARCL2B antibody, ARCL3B antibody, P5C antibody, P5CR antibody, PIG45 antibody, PP222 antibody, PRO3 antibody, PYCR antibody, zgc:73112 antibody, pyrroline-5-carboxylate reductase family, member 1 L homeolog antibody, pyrroline-5-carboxylate reductase 1 antibody, pyrroline-5-carboxylate reductase 1a antibody, pycr1.L antibody, PYCR1 antibody, Pycr1 antibody, pycr1a antibody

Background: This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion.

Molecular Weight: 33361

Gene ID: 5831

NCBI Accession: NP_001269209, NP_001269210, NP_008838, NP_722546

UniProt: P32322