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PYCR1 antibody (C-Term)

PYCR1 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB24671 unconjugated
Catalog No. ABIN653849
  • Target See all PYCR1 Antibodies
    PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))
    Binding Specificity
    • 9
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 291-319, C-Term
    Reactivity
    • 35
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 33
    • 2
    Rabbit
    Clonality
    • 35
    Polyclonal
    Conjugate
    • 21
    • 4
    • 4
    • 4
    • 1
    • 1
    This PYCR1 antibody is un-conjugated
    Application
    • 26
    • 19
    • 17
    • 10
    • 6
    • 5
    • 3
    • 2
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PYCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-319 amino acids from the C-terminal region of human PYCR1.
    Clone
    RB24671
    Isotype
    IgG
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Zeng, Zhu, Liao, Zhuo, Yang, Wu, Wang: "Knockdown of PYCR1 inhibits cell proliferation and colony formation via cell cycle arrest and apoptosis in prostate cancer." in: Medical oncology (Northwood, London, England), Vol. 34, Issue 2, pp. 27, (2017) (PubMed).

  • Target
    PYCR1 (Pyrroline-5-Carboxylate Reductase 1 (PYCR1))
    Alternative Name
    PYCR1 (PYCR1 Products)
    Background
    This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion.
    Molecular Weight
    33361
    Gene ID
    5831
    NCBI Accession
    NP_001269209, NP_001269210, NP_008838, NP_722546
    UniProt
    P32322
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