Cadherin 20 antibody (N-Term)

Catalog No. ABIN653827

Product Details anti-Cadherin 20 Antibody

Target: Cadherin 20 (CDH20)

Binding Specificity: AA 111-140, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cadherin 20 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CDH20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-140 amino acids from the N-terminal region of human CDH20.

Clone: RB23437

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Cadherin 20

Target: Cadherin 20 (CDH20)

Alternative Name: CDH20 (CDH20 Products)

Synonyms: Cdh7 antibody, Cad20 antibody, CDH7L3 antibody, cadherin 20 antibody, cadherin 20 L homeolog antibody, cadherin 20, type 2 antibody, Cdh20 antibody, cdh20.L antibody, CDH20 antibody

Background: This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.

Molecular Weight: 88993

Gene ID: 28316

NCBI Accession: NP_114097

UniProt: Q9HBT6