PLA2G7 antibody (AA 200-228)

Catalog No. ABIN653776

Product Details anti-PLA2G7 Antibody

Target: PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))

Binding Specificity: AA 200-228

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2G7 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PLA2G7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the Central region of human PLA2G7.

Clone: RB21322

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:10~50. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-PLA2G7 antibody (ABIN653776)

Bouchareb, Mahmut, Nsaibia, Boulanger, Dahou, Lépine, Laflamme, Hadji, Couture, Trahan, Pagé, Bossé, Pibarot, Scipione, Romagnuolo, Koschinsky, Arseneault, Marette, Mathieu: "Autotaxin Derived From Lipoprotein(a) and Valve Interstitial Cells Promotes Inflammation and Mineralization of the Aortic Valve." in: Circulation, (2015) (PubMed).

Target Details for PLA2G7

Target: PLA2G7 (Lp-PLA2) (Lipoprotein-Associated phospholipase A2 (Lp-PLA2))

Alternative Name: PLA2G7 (Lp-PLA2 Products)

Synonyms: LDL-PLA2 antibody, LP-PLA2 antibody, PAFAD antibody, PAFAH antibody, Lp-PLA2 antibody, PAF-AH antibody, R75400 antibody, zgc:77563 antibody, phospholipase A2 group VII antibody, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) antibody, PLA2G7 antibody, Pla2g7 antibody, pla2g7 antibody

Background: The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency.

Molecular Weight: 50077

Gene ID: 7941

NCBI Accession: NP_001161829, NP_005075

UniProt: Q13093

Pathways: Peptide Hormone Metabolism