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HDAC2 antibody (AA 410-439)

HDAC2 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB24526 unconjugated
Catalog No. ABIN653718
  • Target See all HDAC2 Antibodies
    HDAC2 (Histone Deacetylase 2 (HDAC2))
    Binding Specificity
    • 29
    • 15
    • 13
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 410-439
    Reactivity
    • 122
    • 87
    • 61
    • 12
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Human
    Host
    • 107
    • 12
    • 3
    • 1
    Rabbit
    Clonality
    • 101
    • 22
    Polyclonal
    Conjugate
    • 65
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This HDAC2 antibody is un-conjugated
    Application
    • 69
    • 44
    • 38
    • 31
    • 28
    • 27
    • 22
    • 17
    • 16
    • 11
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Predicted Reactivity
    C, M
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This HDAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 410-439 amino acids from the Central region of human HDAC2.
    Clone
    RB24526
    Isotype
    Ig Fraction
    Top Product
    Discover our top product HDAC2 Primary Antibody
  • Application Notes
    IF: 1:10~50. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Leucker, Nomura, Kim, Bhatta, Wang, Wecker, Jandu, Santhanam, Berkowitz, Romer, Pandey: "Cystathionine γ-lyase protects vascular endothelium: a role for inhibition of histone deacetylase 6." in: American journal of physiology. Heart and circulatory physiology, Vol. 312, Issue 4, pp. H711-H720, (2017) (PubMed).

  • Target
    HDAC2 (Histone Deacetylase 2 (HDAC2))
    Alternative Name
    HDAC2 (HDAC2 Products)
    Synonyms
    HD2 antibody, RPD3 antibody, YAF1 antibody, D10Wsu179e antibody, Yy1bp antibody, mRPD3 antibody, HISTONE DEACETYLASE antibody, T1N24.9 antibody, T1N24_9 antibody, histone deacetylase 2 antibody, histone deacetylase 2 antibody, histone deacetylase 2 S homeolog antibody, HDAC2 antibody, Hdac2 antibody, hdac2.S antibody, HDA2 antibody
    Background
    This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events.
    Molecular Weight
    55364
    Gene ID
    3066
    NCBI Accession
    NP_001518
    UniProt
    Q92769
    Pathways
    Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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