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STING/TMEM173 antibody (C-Term)

TMEM173 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB24462 unconjugated
Catalog No. ABIN653703
  • Target See all STING/TMEM173 (TMEM173) Antibodies
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    Binding Specificity
    • 15
    • 12
    • 10
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 311-340, C-Term
    Reactivity
    • 65
    • 25
    • 20
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 79
    • 4
    Rabbit
    Clonality
    • 66
    • 17
    Polyclonal
    Conjugate
    • 41
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This STING/TMEM173 antibody is un-conjugated
    Application
    • 47
    • 26
    • 18
    • 16
    • 13
    • 13
    • 11
    • 9
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This TMEM173 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-340 amino acids from the C-terminal region of human TMEM173.
    Clone
    RB24462
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TMEM173 Primary Antibody
  • Application Notes
    WB: 1:1000. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    Alternative Name
    TMEM173 (TMEM173 Products)
    Background
    Acts as a facilitator of innate immune signaling. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
    Molecular Weight
    42193
    Gene ID
    340061
    NCBI Accession
    NP_938023
    UniProt
    Q86WV6
    Pathways
    Activation of Innate immune Response
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