Uroplakin 1B antibody (AA 159-188)

Catalog No. ABIN653680

Product Details anti-Uroplakin 1B Antibody

Target: Uroplakin 1B (UPK1B)

Binding Specificity: AA 159-188

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 1B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UPK1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-188 amino acids from the Central region of human UPK1B.

Clone: RB24302

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Uroplakin 1B

Target: Uroplakin 1B (UPK1B)

Alternative Name: UPK1B (UPK1B Products)

Synonyms: MGC81971 antibody, upk1b antibody, MGC81493 antibody, UPK1B antibody, TSPAN20 antibody, UPIB antibody, UPK1 antibody, AI413235 antibody, Tspan20 antibody, UPIb antibody, Upk1 antibody, uroplakin 1B antibody, uroplakin 1B S homeolog antibody, uroplakin 1A S homeolog antibody, UPK1B antibody, upk1b.S antibody, upk1a.S antibody, upk1b antibody, Upk1b antibody

Background: UPK1B is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions.

Molecular Weight: 29643

Gene ID: 7348

NCBI Accession: NP_008883

UniProt: O75841