SLCO1B1 antibody (AA 267-293)

Catalog No. ABIN653562

Product Details anti-SLCO1B1 Antibody

Target: SLCO1B1 (Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1))

Binding Specificity: AA 267-293

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLCO1B1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This SLCO1B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-293 amino acids from the Central region of human SLCO1B1.

Clone: RB23028

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:500. WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for SLCO1B1

Target: SLCO1B1 (Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1))

Alternative Name: SLCO1B1 (SLCO1B1 Products)

Synonyms: HBLRR antibody, LST-1 antibody, LST1 antibody, OATP-C antibody, OATP1B1 antibody, OATP2 antibody, OATPC antibody, SLC21A6 antibody, SLCO1B1 antibody, solute carrier organic anion transporter family member 1B1 antibody, SLCO1B1 antibody, LOC100011628 antibody, LOC100448597 antibody

Background: AP9609c is a liver-specific member of the organic anion transporter family. This protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.

Molecular Weight: 76449

Gene ID: 10599

NCBI Accession: NP_006437

UniProt: Q9Y6L6