TIFA antibody (N-Term)

Catalog No. ABIN653538

Product Details anti-TIFA Antibody

Target: TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))

Binding Specificity: AA 52-79, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIFA antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TIFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-79 amino acids from the N-terminal region of human TIFA.

Clone: RB24815

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TIFA

Target: TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))

Alternative Name: TIFA (TIFA Products)

Synonyms: TIFA antibody, xtifa antibody, T2BP antibody, T6BP antibody, TIFAA antibody, T2bp antibody, Ab2-389 antibody, TRAF interacting protein with forkhead associated domain antibody, TRAF-interacting protein with forkhead-associated domain antibody, TRAF-interacting protein with forkhead-associated domain S homeolog antibody, TIFA antibody, tifa antibody, Tifa antibody, tifa.S antibody

Background: Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.

Molecular Weight: 21445

Gene ID: 92610

NCBI Accession: NP_443096

UniProt: Q96CG3