Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CHMP4B antibody (N-Term)

CHMP4B Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB24088 unconjugated
Catalog No. ABIN653481
  • Target See all CHMP4B Antibodies
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    Binding Specificity
    • 15
    • 7
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    AA 51-79, N-Term
    Reactivity
    • 44
    • 22
    • 14
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Host
    • 43
    • 1
    Rabbit
    Clonality
    • 43
    • 1
    Polyclonal
    Conjugate
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CHMP4B antibody is un-conjugated
    Application
    • 19
    • 19
    • 18
    • 13
    • 13
    • 11
    • 4
    • 3
    • 3
    • 3
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    C, Zf, M, X
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This CHMP4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-79 amino acids from the N-terminal region of human CHMP4B.
    Clone
    RB24088
    Isotype
    Ig Fraction
    Top Product
    Discover our top product CHMP4B Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Hu, Jiang, Chen, Wei, Zhang, Zhao, Ni, Lu, Wan: "High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma." in: Tumour biology, Vol. 36, Issue 4, pp. 2569-81, (2015) (PubMed).

  • Target
    CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))
    Alternative Name
    CHMP4B (CHMP4B Products)
    Synonyms
    C20orf178 antibody, CHMP4A antibody, CTPP3 antibody, CTRCT31 antibody, SNF7 antibody, SNF7-2 antibody, Shax1 antibody, VPS32B antibody, Vps32-2 antibody, dJ553F4.4 antibody, 2010012F05Rik antibody, C76846 antibody, Snf7-2 antibody, RGD1309846 antibody, RGD1565889 antibody, CHMP4b antibody, chmp4b antibody, chmp4b.S antibody, CHMP4c antibody, c20orf178 antibody, wu:fc96b02 antibody, zgc:55566 antibody, charged multivesicular body protein 4B antibody, charged multivesicular body protein 4Ba antibody, charged multivesicular body protein 4B L homeolog antibody, charged multivesicular body protein 4Bb antibody, CHMP4B antibody, Chmp4b antibody, chmp4ba antibody, chmp4b.L antibody, chmp4bb antibody
    Background
    CHMP4B is a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies.
    Molecular Weight
    24950
    Gene ID
    128866
    NCBI Accession
    NP_789782
    UniProt
    Q9H444
You are here:
Support