PREX1 antibody (AA 567-594)

Catalog No. ABIN653415

Product Details anti-PREX1 Antibody

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Binding Specificity: AA 567-594

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PREX1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PREX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-594 amino acids from the Central region of human PREX1.

Clone: RB22416

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PREX1

Target: PREX1 (Phosphatidylinositol-3,4,5-Trisphosphate-Dependent Rac Exchange Factor 1 (PREX1))

Alternative Name: PREX1 (PREX1 Products)

Synonyms: MGC68772 antibody, P-REX1 antibody, G630042G04 antibody, Setd6 antibody, RGD1306534 antibody, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 L homeolog antibody, phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 antibody, phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 antibody, prex1.L antibody, PREX1 antibody, prex1 antibody, Prex1 antibody

Background: The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.

Gene ID: 57580

NCBI Accession: NP_065871

UniProt: Q8TCU6

Pathways: Regulation of Actin Filament Polymerization