IL2RG antibody (N-Term)

Catalog No. ABIN653403

Product Details anti-IL2RG Antibody

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Binding Specificity: AA 76-101, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL2RG antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IL2RG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-101 amino acids from the N-terminal region of human IL2RG.

Clone: RB22117

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:25. WB: 1:1000. WB: 1:2000. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for IL2RG

Target: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Alternative Name: IL2RG (IL2RG Products)

Synonyms: Ab2-183 antibody, Cd132 antibody, CD132 antibody, CIDX antibody, IL-2RG antibody, IMD4 antibody, P64 antibody, SCIDX antibody, SCIDX1 antibody, [g]c antibody, gamma(c) antibody, gc antibody, interleukin 2 receptor subunit gamma antibody, interleukin 2 receptor subunit gamma L homeolog antibody, interleukin 2 receptor, gamma chain antibody, IL2RG antibody, il2rg.L antibody, Il2rg antibody

Background: IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

Molecular Weight: 42287

Gene ID: 3561

NCBI Accession: NP_000197

UniProt: P31785

Pathways: JAK-STAT Signaling, Growth Factor Binding