HBa2 antibody (AA 100-128)

Catalog No. ABIN653363

Product Details anti-HBa2 Antibody

Target: HBa2 (Hemoglobin, alpha 2 (HBa2))

Binding Specificity: AA 100-128

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBa2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Predicted Reactivity: Pr

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HBA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 100-128 amino acids from the Central region of human HBA2.

Clone: RB24041

Isotype: IgG

Application Details

Application Notes: WB: 1:2000. WB: 1:1000. FC: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for HBa2

Target: HBa2 (Hemoglobin, alpha 2 (HBa2))

Alternative Name: HBA2 (HBa2 Products)

Synonyms: HBAM antibody, Hba-a1 antibody, Hba-a2 antibody, hba2 antibody, HBH antibody, hba5 antibody, HBA2 antibody, alpha globin antibody, HBA1 antibody, HBAI antibody, HBAII antibody, Glnc1 antibody, GloA antibody, hemoglobin, alpha 1 antibody, hemoglobin subunit alpha 1 S homeolog antibody, hemoglobin subunit alpha 2 antibody, hemoglobin subunit alpha 2 L homeolog antibody, hemoglobin subunit mu antibody, hemoglobin, alpha 2 antibody, hemoglobin subunit alpha-2-like antibody, hemoglobin alpha, adult chain 1 antibody, hemoglobin alpha, adult chain 2 antibody, Hba1 antibody, hba1.S antibody, HBA2 antibody, hba2.L antibody, HBM antibody, HBA antibody, Hba2 antibody, LOC102168959 antibody, Hba-a1 antibody, Hba-a2 antibody

Background: HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97 % of the total hemoglobin, alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3 % of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1, some nondeletion alpha thalassemias have also been reported.

Molecular Weight: 15258

Gene ID: 3039

NCBI Accession: NP_000508, NP_000549

UniProt: P69905