CHIA antibody (N-Term)

Catalog No. ABIN653343

Product Details anti-CHIA Antibody

Target: CHIA (Chitinase, Acidic (CHIA))

Binding Specificity: AA 20-47, N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHIA antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CHIA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-47 amino acids from the N-terminal region of human CHIA.

Clone: RB23130

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for CHIA

Target: CHIA (Chitinase, Acidic (CHIA))

Alternative Name: CHIA (CHIA Products)

Synonyms: chia-a antibody, AMCASE antibody, CHIT2 antibody, TSA1902 antibody, 2200003E03Rik antibody, AMCase antibody, YNL antibody, CHIA antibody, chioIIa antibody, fa55g10 antibody, wu:fa55g10 antibody, zgc:63792 antibody, acidic mammalian chitinase antibody, chitinase, acidic antibody, chitinase, acidic S homeolog antibody, chitinase-M31, acidic antibody, chitinase, acidic 1 antibody, chitinase, acidic.4 antibody, LOC703284 antibody, CHIA antibody, LOC100600050 antibody, chia.S antibody, CHIA-M31 antibody, Chia1 antibody, Chia antibody, chia.4 antibody

Background: CHIA degrades chitin and chitotriose. May participate in the defense against nematodes and other pathogens. There are 3 named isoforms produced by alternative splicing. CHIA is induced via a T helper-2 (Th2)-specific, interleukin-13-mediated pathway in epithelial cells and macrophages. CHIA may be an important mediator of IL13-induced responses in Th2-dominated disorders such as asthma. CHIA hydrolysis N-acetyl-beta-D-glucosaminide 1,4-beta-linkages in chitin and chitodextrins.

Molecular Weight: 52271

Gene ID: 27159

NCBI Accession: NP_001035713, NP_001244930, NP_001244931, NP_001244932, NP_001244933, NP_001244934, NP_068569, NP_970615

UniProt: Q9BZP6