Melatonin Receptor 1A antibody (AA 209-239)

Catalog No. ABIN653231

The Rabbit Polyclonal anti-Melatonin Receptor 1A antibody is suitable to detect Melatonin Receptor 1A in samples from Human. It has been validated for WB and FACS.

Quick Overview for Melatonin Receptor 1A antibody (AA 209-239) (ABIN653231)

Target: Melatonin Receptor 1A (MTNR1A)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB23653

Product Details anti-Melatonin Receptor 1A Antibody

Binding Specificity: AA 209-239

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MTNR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-239 amino acids from the Central region of human MTNR1A.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:500. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Melatonin Receptor 1A

Target: Melatonin Receptor 1A (MTNR1A)

Alternative Name: MTNR1A

Background: MTNR1A encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Molecular Weight: 39375

Gene ID: 4543

NCBI Accession: NP_005949

UniProt: P48039