F-Box Protein 3 antibody (C-Term)

Catalog No. ABIN653142

Product Details anti-F-Box Protein 3 Antibody

Target: F-Box Protein 3 (FBXO3)

Binding Specificity: AA 395-422, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This F-Box Protein 3 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Predicted Reactivity: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FBXO3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-422 amino acids from the C-terminal region of human FBXO3.

Clone: RB23911

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-F-Box Protein 3 antibody (ABIN653142)

Schlierf, Altmann, Quancard, Jefferson, Assenberg, Renatus, Jones, Hassiepen, Schaefer, Kiffe, Weiss, Wiesmann, Sedrani, Eder, Martoglio: "Targeted inhibition of the COP9 signalosome for treatment of cancer." in: Nature communications, Vol. 7, pp. 13166, (2018) (PubMed).

Target Details for F-Box Protein 3

Target: F-Box Protein 3 (FBXO3)

Alternative Name: FBXO3 (FBXO3 Products)

Synonyms: FBA antibody, FBX3 antibody, 1200002G09Rik antibody, 1700026K02Rik antibody, AI046358 antibody, Fba antibody, zgc:112485 antibody, DKFZp459H187 antibody, F-box protein 3 antibody, F-box protein 3 S homeolog antibody, FBXO3 antibody, Fbxo3 antibody, fbxo3.S antibody, fbxo3 antibody

Background: FBXO3 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs.

Molecular Weight: 54561

Gene ID: 26273

NCBI Accession: NP_036307, NP_208385

UniProt: Q9UK99