MUTYH antibody (AA 341-367)

Catalog No. ABIN653106

Product Details anti-MUTYH Antibody

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Binding Specificity: AA 341-367

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUTYH antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MUTYH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-367 amino acids from the Central region of human MUTYH.

Clone: RB17460

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for MUTYH

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Alternative Name: MUTYH (MUTYH Products)

Background: MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.

Molecular Weight: 60069

Gene ID: 4595

NCBI Accession: NP_001041636, NP_001041637, NP_001041638, NP_001041639, NP_001121897, NP_036354

UniProt: Q9UIF7

Pathways: DNA Damage Repair