DUSP2 antibody (C-Term)

Catalog No. ABIN653027

Product Details anti-DUSP2 Antibody

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Binding Specificity: AA 262-290, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This DUSP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the C-terminal region of human DUSP2.

Clone: RB17124

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for DUSP2

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Alternative Name: DUSP2 (DUSP2 Products)

Synonyms: zgc:91929 antibody, wu:fj40g04 antibody, PAC-1 antibody, PAC1 antibody, dual specificity phosphatase 2 antibody, dusp2 antibody, DUSP2 antibody, Dusp2 antibody

Background: DUSP2 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.

Molecular Weight: 34400

Gene ID: 1844

NCBI Accession: NP_004409

UniProt: Q05923