DZIP1 antibody (AA 568-596)

Catalog No. ABIN652872

Product Details anti-DZIP1 Antibody

Target: DZIP1 (DAZ Interacting Protein 1 (DZIP1))

Binding Specificity: AA 568-596

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DZIP1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DZIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 568-596 amino acids from the Central region of human DZIP1.

Clone: RB23724

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-DZIP1 antibody (ABIN652872)

Zhang, Wang, Xu, Yang, Zhuang, Wang, Ren, Cheng, Jiang, Zhang: "DAZ-interacting Protein 1 (Dzip1) Phosphorylation by Polo-like Kinase 1 (Plk1) Regulates the Centriolar Satellite Localization of the BBSome Protein during the Cell Cycle." in: The Journal of biological chemistry, Vol. 292, Issue 4, pp. 1351-1360, (2017) (PubMed).

Zhang, Zhang, Wang, Wang, Chi, Jiang, Zhang: "GSK3?-Dzip1-Rab8 cascade regulates ciliogenesis after mitosis." in: PLoS biology, Vol. 13, Issue 4, pp. e1002129, (2015) (PubMed).

Target Details for DZIP1

Target: DZIP1 (DAZ Interacting Protein 1 (DZIP1))

Alternative Name: DZIP1 (DZIP1 Products)

Synonyms: dzip antibody, dzipt1 antibody, DZIP1 antibody, MGC142440 antibody, MGC146244 antibody, rp11-23e3.3 antibody, 2510025K24Rik antibody, 2810422M04Rik antibody, mKIAA0996 antibody, DZIP antibody, DZIPt1 antibody, igu antibody, igu/dzip1 antibody, si:dz52i16.1 antibody, DAZ interacting zinc finger protein 1 antibody, DAZ interacting zinc finger protein 1 L homeolog antibody, DAZ interacting protein 1 antibody, DZIP1 antibody, dzip1.L antibody, dzip1 antibody, Dzip1 antibody

Background: DZIP1 may participate in spermatogenesis via its interaction with DAZ. Isoform 1 and isoform 2 interact with DAZ proteins. DZIP1 may also participate in a RNA-binding complex that functions in both ES cells and germ cells. There are three named isoforms.

Molecular Weight: 98664

Gene ID: 22873

NCBI Accession: NP_055749, NP_945319

UniProt: Q86YF9

Pathways: Hedgehog Signaling, Protein targeting to Nucleus