This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This AMOTL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-152 amino acids from the Central region of human AMOTL2.
AMOTL2
Reactivity: Human
ELISA, WB, IHC
Host: Rabbit
unconjugated
Application Notes
WB: 1:2000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Proszynski, Sanes: "Amotl2 interacts with LL5?, localizes to podosomes and regulates postsynaptic differentiation in muscle." in: Journal of cell science, Vol. 126, Issue Pt 10, pp. 2225-35, (2013) (PubMed).
AMOTL2 is a protein that binds angiostatin, a circulating inhibitor of the formation of new blood vessels (angiogenesis). Angiomotin mediates angiostatin inhibition of endothelial cell migration and tube formation in vitro. The protein encoded by this gene is related to angiomotin and is a member of the motins protein family.