RGS1 antibody (N-Term)

Catalog No. ABIN652704

Product Details anti-RGS1 Antibody

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Binding Specificity: AA 19-45, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RGS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human RGS1.

Clone: RB22894

Isotype: IgG

Application Details

Application Notes: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for RGS1

Target: RGS1 (Regulator of G-Protein Signaling 1 (RGS1))

Alternative Name: RGS1 (RGS1 Products)

Synonyms: 1R20 antibody, BL34 antibody, IER1 antibody, IR20 antibody, RGS1 antibody, 1r20 antibody, bl34 antibody, ier1 antibody, ir20 antibody, regulator of G protein signaling 1 antibody, regulator of G-protein signaling 1 antibody, regulator of G-protein signaling 1 S homeolog antibody, Regulator of G-protein signaling 1 antibody, RGS1 antibody, Rgs1 antibody, rgs1.S antibody, rgs1 antibody

Background: RGS1 is a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Molecular Weight: 23858

Gene ID: 5996

NCBI Accession: NP_002913

UniProt: Q08116

Pathways: MAPK Signaling, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events