FLCN antibody (AA 325-354)

Catalog No. ABIN652602

Product Details anti-FLCN Antibody

Target: FLCN (Folliculin (FLCN))

Binding Specificity: AA 325-354

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLCN antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This FLCN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-354 amino acids from the Central region of human FLCN.

Clone: RB20959

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for FLCN

Target: FLCN (Folliculin (FLCN))

Alternative Name: FLCN (FLCN Products)

Synonyms: FLCN antibody, flcn antibody, wu:fe38g11 antibody, zgc:136982 antibody, AU014660 antibody, B430214A04Rik antibody, Bhd antibody, FLCL antibody, BHD antibody, folliculin antibody, folliculin S homeolog antibody, FLCN antibody, flcn antibody, flcn.S antibody, Flcn antibody

Target Type: Amino Acid

Background: FLCN may play a role in the pathogenesis of an uncommon form of kidney cancer through its association with an inherited disorder of the hair follicle (fibrofolliculomas). FLCN may be a tumor suppressor. May be involved in colorectal tumorigenesis. It may be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways.

Molecular Weight: 64473

Gene ID: 201163

NCBI Accession: NP_653207, NP_659434

UniProt: Q8NFG4

Pathways: Cell-Cell Junction Organization